Stem Cell Guidelines Comment Form

The NIH has released draft guidelines for embryonic stem cell research and is currently gathering public comments.

Take action! Add your voice to the debate by submitting a comment.

Comments Deadline:  11:00pm EST on May 26, 2009. 

NIH Comment Form

When you're done, leave a comment here and let us know you shared your opinion with the NIH. And if you want, tell us your opinion!

These draft Guidelines would allow funding for research using human embryonic stem cells that were derived from embryos created by in vitro fertilization (IVF) for reproductive purposes and were no longer needed for that purpose. Funding will continue to be allowed for human stem cell research using adult stem cells and induced pluripotent stem cells.

Specter for the Cure

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Senator Arlen Specter intends to build a "bridge over the valley of death."

Senator Specter has launched “Specter for the Cure”, a bold new initiative to reform our government’s medical research efforts, cut red tape and untangle the hope for accelerated cures.

 

Senator Arlen Specter on Stem Cells

  • As part of the American Recovery and Reinvestment Act, Sen. Specter successfully included a provision to increase the funding to the National Institutes of Health by $6.5 billion, for a total of $10 billion in the legislation.

 

  • Sen. Specter has held 20 hearings directly relating to stem cell research, chairing the LHHS Appropriations Subcommittee's first hearing regarding stem cells on December 2, 1998.

 

  • During the 109th Congress, the house companion bill to S.471, the Stem Cell Research Enhancement Act, was passed by Congress, but vetoed by President Bush. The vote to override the veto in the House failed. The legislation would expand the number of stem cell lines that are eligible for federally funded research, thereby accelerating scientific progress toward cures and treatments for a wide range of diseases and debilitating health conditions.
    In the 110th Congress, Sen. Specter is a lead cosponsor of S. 5, the Stem Cell Research Enhancement Act, which is identical to the legislation in the 109th Congress. The Stem Cell Research Enhancement Act was passed by Congress, but a vote to override the veto in the house again failed.

 

  • Sen. Specter was a lead cosponsor of the Stem Cell Therapeutic and Research Act, which was signed into law in 2005. The legislation directed the Secretary of Health and Human Services to enter into contracts with qualified cord blood stem cell banks to assist in the establishment, provision, and maintenance of a National Cord Blood Stem Cell Banks Network. As Chairman and Ranking Member of the LHHS Appropriations Subcommittee, Sen. Specter has worked to provide funding for this effort. For fiscal year 2008, $8.8 million was provided for cord blood programs, an increase of $6 million from fiscal year 2007.

Senator Arlen Specter: Stem Cell Champion

specter This post is a tribute to Senate Republican Arlen Specter, a man who is crossing party lines to stand up for what he believes in - namely, stem cell research.

Specter recently proposed the creation of a new agency known as the Cures Acceleration Network that will facilitate the development of new treatments for cancer, multiple sclerosis, diabetes, and other diseases by awarding grants to cash-starved biotech companies. <-- Investors, this is where you get excited.

"Without adequate funding, these companies will be unable to take these products to the development state, the basic research done by the NIH (National Institutes of Health) will be lost, and many patients will die waiting for drugs and devices to give them a better quality of life," Specter said.

The Senator from Pennsylvania has recently been at odds with some of his fellow Republicans after securing stimulus package money for the NIH. What his peers will soon learn, however, is that Specter's bold actions have put him in favor with many stem cell advocates and they will undoubtedly secure his re-election next year, or so we’d like to believe here at Stem Cell Weblog.

"I believe that we can live not only longer lives, but healthier lives, by harnessing and applying the genius of our biomedical research community and getting about the task of accelerating cures," said Specter, a two-time cancer survivor, in remarks prepared for a Chicago speech to physicians and researchers.

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Drudge Report Headline: ‘I CAN CLONE A HUMAN BEING’

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The topic of embryonic cloning made its way to Drudge Report’s top headline on Tuesday, March 21 in a late-night update made to the site around 11 p.m.

The article it linked to claims controversial fertility doctor Panayiotis Zavos cloned 14 human embryos and transferred 11 of them into four women.

Here is the Q & A taken from that very interesting article:

Q. What does he claim to have done?

A. Panayiotis Zavos says he has created 14 human embryos and transferred 11 of them into the wombs of four women. Some of these embryos only developed to the four-cell stage before being transferred, but some developed to the 32-cell stage, called a morula. He also claims to have created human-bovine hybrid clones by transferring the cells of dead people into the empty eggs of cows. However, these hybrid embryos were used for research purposes and were not transferred to the womb.

Q. How does this compare to scientists' previous achievements?

A. Other scientists have created human-cloned embryos but not for the purposes of transferring them to wombs in order for women to give birth to babies. Those researchers created cloned human embryos in the test tube to extract stem cells for research. Dr Zavos has gone further (and broken a taboo) by creating embryos specifically for human reproduction, and he has attempted to create a viable pregnancy by transferring the cloned embryos into women.

Q. Hasn't he made similar claims before?

A. In 2004, Dr Zavos claimed to have transferred a cloned human embryo into a woman's womb but did not produce hard evidence. He has now produced more cloned human embryos, some at an advanced stage, and transferred them into the wombs of three more women. An independent documentary maker vouches for him.

Q. Why is this such a controversial thing to do?

A. Studies on animal cloning have shown time and time again that it is unsafe. The cloned animals suffer a higher-than-normal risk of severe developmental problems and the pregnancies often end in miscarriage. Mainstream scientists believe cloning is too dangerous to be used on humans.

Q. How likely is it that he will succeed?

A. He is determined to succeed and has a long line of people eager to sign up to his cloning programme, at a cost of between $45,000 and $75,000. Cloning attempts in other species, including primates, suggest there is no insuperable barrier to cloning humans.

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We must wait and see if this story is indeed true, but we must not forget the false story of the Korean stem cell researcher who claimed to successfully create the world’s first cloned human embryos in 2005. That story can be found here

If this is true, it would be a remarkable breakthrough for the stem cell research industry since cloning a human embryo could provide a new (and even more debated) source for stem cell researchers (If the NIH drafted new guidelines to make it legal) to conduct embryonic stem cell research.

On a side note, the photo used in the Drudge Report headline was originally made available by Advanced Cell Technology in 2006. It shows a single cell being removed from a human embryo to be used in generating embryonic stem cells for scientific research.

The Top Stem Cell Stock Blogs

Stem-cell stocks have become a popular topic for discussion since the beginning of 2009, and a few bloggers have risen to the occasion to meet public demand for stem cell information. Heck, some are even calling 2009 The Year of the Stem Cell. This post is a tribute to them, and a resource for you.

At the beginning of January 2009, some stem cell companies were barely able to pay the bills after being shunned by the U.S. government for many years, so conducting top-tier stem cell research was not always possible. In the same month, stem cell stock prices soared in anticipation of Barack Obama's executive order that allowed federal funding for embryonic stem cell research. For example, Advanced Cell Technology, Inc. (ACTC) went from trading around 4 cents on January 2nd to 29 cents on January 26th, creating windfall profits for investors and national attention for the entire sector. Since then, most stem cell stocks have retreated, others maintained momentum, and some have gone even higher.  

Just like with all investments, different factors contribute to the price of a stock at any given moment. The exchange (Pink Sheets, AMEX, NASDAQ, etc.), patents, debt, share structure, management, and speculation (especially with Pink Sheets) can, and do, influence the price a stock is trading at. As a new technology with an unknown future, investing in stem cell companies can be risky, but extremely rewarding down the road if and when advancements lead to commercialized therapies across the globe. Before investing in anything, always keep in mind The Five Commandments of Trading for the Unenlightened Investor.

Here are the best stem cell blogs and sites that I have found to be most useful when researching information on stem cell companies and stocks:

 

Stem Cell Stock Informer

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Stem Cell Stock Informer is a blog maintained by veteran blogger Lawrence "Jose" Sinclair and offers a daily recap of the stem cell market. These recaps are great for on-the-go investors wanting to know how many stem cell stocks were up and down for the day, how they compare to the overall market, and what may be influencing these trends in a concise, to-the-point update.

For the most part, three sections in a post cover it all: A summary for the day, "Big Winners," and "Biggest Drops."  More detailed posts can be found throughout the site covering companies like Geron and other important investor-related topics such as relevant public & private institutions and ongoing policy changes. There are also useful links to various resources and even a long list of stem cell stock tickers.

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Making Money Trading Stem Cell Company Stocks 

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Making Money Trading Stem Cell Company Stocks may be published on a simple Blogger layout, but this is a case where content truly is king.

The site is updated weekly with an in-depth analysis of the stem cell market for "the week that was."

These updates include a summary, top performers, worst performers, current prices for stem cell stocks with a market cap over and under 50 million, and catalysts for the week. This blog is a hidden gem for stem cell investors, as it is a little more under the radar than the more prominent sites you will find on the first page after a Google search.

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The International Stem Cell Business Directory

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Stem-Cell-Companies.com is a good resource for anyone seeking thorough information on domestic and international stem cell companies.

As of this posting, the site hasn't been updated since November 13, 2008, which may mean it is due for an update to stay current, but it still provides a valuable directory with over 80 companies listed from all over the globe.

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I haven't found too many blogs or sites dedicated solely to stem cell stocks, so please leave a comment and let me know if I've missed one. I will keep this updated as new information becomes available.

Also, please leave a comment and let me know what you thought about these sites and what you would like to see added to them as an investor. Since the stem cell market is just beginning to gain traction, your input can prove to be an invaluable resource for webmasters and bloggers around the globe.

Help them help you!

Please take note that I am not affiliated with these sites in any way other than as a fellow blogger on the World Wide Web. I don't endorse any stem cell company and urge you to do your due diligence before making any financial decisions.

Good luck, and happy trading! 

Florida Loses Stem Cell Battle

floridahouseofrepsHouse budget chief Rep. David Rivera, R-Miami, put language in the House budget that bans the use of any state funds to support embryonic stem cell research, and it passed.

After an emotional debate, an amendment offered by House Democratic Leader Franklin Sands, D-Weston, to salvage the possibility of state funding for embryonic stem cell research in Florida just went down.

Florida is now one of  the states where unused embryos found at in-vitro fertilization clinics will be destroyed rather than used to help make people's lives better through stem cell research.

E-mail  members from the Florida House of Representatives and voice your opinion about this issue. If more people pay attention, they may start to re-think their stance on important issues like stem cell research in enough time to be re-elected.

The Sunshine State does not look too bright for people in need of stem cell therapy.

Dendreon Corporation - A Dream Come True for Investors and Patients

April 14 - Tuesday was a shareholders dream come true for those invested in Dendreon Corporation (DNDN). After phase III clinical trials for the company's prostate cancer vaccine Provenge showed to increase the survival rate of patients, the company's share price soared over 175% within hours of trading.

"We've been saying for years the drug worked, we just did not know how many trials it would take to prove it to the FDA. This morning, we received our answer and it is a great one for guys everywhere with prostate cancer," said David Miller of Biotech Monthly.

The IMPACT study was designed to reduce the risk of death in prostate cancer patients by 22%. Details of the study will be presented at a medical conference on April 28. Previous studies of Provenge showed the drug to prolong survival by 4.5 months over placebo.

"Survival is the gold standard outcome for oncology clinical trials, and overall survival was the primary endpoint of the IMPACT trial. The positive results from this landmark study provide confirmatory evidence demonstrating that treatment with PROVENGE may prolong survival," said Dendreon CEO Mitch Gold, in a statement.

On a conference call Tuesday morning, Gold said that the Provenge results from the IMPACT study were "unambiguous" and "consistent" with previous studies of the cancer vaccine.

Dendreon's next move will be to submit the results to the U.S. Food and Drug Administration in the middle of 2009 and an approval decision could be made as early as the second quarter of 2010.

To all who benefit from this: Congratulations!

Michael J. Fox interview on Larry King Live set to air Thursday night

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In an interview scheduled to air Thursday night on CNN, Michael J. Fox sat down with Larry King to discuss stem cell research and other topics including family, acting, and Parkinson’s.

Here are a few excerpts that are currently available.

Larry King: He's founder of The Michael J. Fox Foundation for Parkinson's Research. He's a best-selling author -- the new book is "Always Looking Up." By the way, he has got an ABC special, "Michael J. Fox: Adventures of an Incurable Optimist." It airs on May 7. You remain -- is it easy to be an optimist?

Michael J. Fox: Well, for me it's second nature. It's just the way I look at life. And it's certainly a challenge now for most people to be optimistic, obviously, with all of the troubles we have and the problems that the country is facing.

But I think it's exactly in those times when our optimism kicks in highest gear. I think -- there's an expression that I like that I always use: "Don't wish for a lighter load, wish for broader shoulders." And I think that people are really -- I see a lot of broader shoulders these days, people are really working on the delts, you know?

King: What was it like when you were diagnosed?

Fox: Well, you know, it's hard to describe it, because I was so young, I was 29 years old. And so Parkinson's is not what you expect to hear. I had a twitch in my pinky and I figured it was some kind of nerve damage or I'd done something probably athletic. ... But then I got this diagnosis, and I thought the guy was kidding. And then it was shock, and then I had a certain amount of fear and I started to react to it in certain ways. I started drinking more heavily as a way of self-medicating it.

And it took me -- you know, it's funny, because I sit and talk about "Always Looking Up" and being optimistic, and accept the losses and move on or find new gains, but it took me about seven years, I think, to really get to the point where I could tell people about it. ... I was diagnosed in '91, and it wasn't until '98 that I admitted publicly that it was a situation I was facing.

King: It is not life-threatening, is it?

Fox: No. And I would say you don't die from it, but you -- up to now, you'll definitely die with it if you have it. ...

King: Why did you write the book?

Fox: The book was -- I wrote the first book because I had to, I think I had to kind of tell that story just for myself, just kind of to acknowledge all of the work that I had done on getting through that journey.

And then this book was -- I thought about writing another, and I thought about people responding so positively to the optimism in the first book. And so many people wanted to talk to me about that.

So I thought, well, optimism: What is optimism? And so I started to think about it more kind of empirically, writing a book about optimism as a subject, and interviewing researchers about it and talking to people who are optimistic and traveling to places where people are optimistic and all of this stuff. ...

So I had to kind of tell it -- I couldn't tell, talk about optimism without -- and separate it from my experience. I had to make it part of my experience. So then, having done that, and written this book, which is really a memoir of the last 10 years, I still have these questions about optimism.

So I went to ABC and I said, 'There was a thing I was going to do a book on, but I'd like to do a documentary special on.' And they said, great.

And so we've been traveling around, talking to optimists. We went to Bhutan, which is a country in the Himalayas that actually measures its gross national happiness along with its GDP.

King: Really?

Fox: Yes. And it makes decisions on its development as a country based on how to affect the happiness of the people. And the people are uniformly happy. It's amazing. ...

King: Speaking of optimism, in March, President Obama lifted the ban on federal financing for embryonic stem cell research. You've long fought for that. You've got to feel like a -- it has come true.

--------------------------

King: When you act, is it hard?

Fox: Oh, yes. I don't have any access to the same tool kit that I always had. But it's like anything. It's like, you find new ways of doing things. And in those new ways, you maybe are able to do things you couldn't do before in ways you might not have approached before.

And that's my whole kind of philosophy of life is -- in dealing with Parkinson's or any kind of setback or loss, is that if you avoid it or it creates a hole that you try to fill up with other stuff, with your ego and your needs and your wants and your control issues, then you're just going to dig deeper in a hole.

But if you just recognize, 'look, it is what it is' -- now what's around it? I mean, the only thing that I don't have a choice about is whether I have Parkinson's. Everything else I have a choice about.

------------------------------------------

King: Parts of your book are a love letter to your wife, Tracy. Without being saccharine, how important has she been?

Fox: I couldn't have made the journey that I've made without her. And certainly I wouldn't have this family that I have. And three-quarters of our children were born after the diagnosis. And we knew what we were facing, what we were dealing with, and had some sense of what the prospects were, although they've turned out a lot better than we could have imagined.

I mean, I'm 20 years after diagnosis, and there's very little that I don't do now that I used to do. I still travel with my kids, and I'm with them part of the day, every day.
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King: How old are they now?

Fox: My oldest is 19 -- he'll be 20 next month. And the twins are going into high school next year; they are 14. And then I have a 7-year-old.

Michael J. Fox on The Daily Show: Transcript

foxstewart

Michael J. Fox appeared as a guest on The Daily Show with Jon Stewart on Monday (April 6, 2009) to promote his new book Always Looking Up: The Adventures of an Incurable Optimistfoxbook.

Here is the full transcript of that interview where the two discuss Parkinson's disease, stem cell research, and even call out Rush Limbaugh for his stance on stem cell research and his treatment towards Michael J. Fox.

Fox will also appear on Larry King Live Wednesday night (April 8, 2009) and a transcript will be made available here at StemCellWeblog.com shortly after.

--------------

Stewart: Welcome back, my guest tonight, an actor and best-selling author whose new book is called Always Looking Up: The Adventures of an Incurable Optimistalwayslookingup, please welcome back to the program Michael J. Fox!

[Fox appears, crowd applauds]

Stewart: Take a bow! Nicely done. Howdy howdy.

Fox: Cool. You gotta bigger shot than you had the last time I was here.

Stewart: You were here 10 years ago, the very first show that I did.

Fox: Yeah, cause I was on your show at MTV but -

Stewart: Yes

Fox: But yeah I think I was the first guest.

Stewart: The first time I interviewed you was on the MTV show and you told me a story about doing rattle snake venom shots.

Fox: No, Cobra. Cobra.

Stewart: That's it, Cobra venom shots!

Fox: I was in Thailand doing Casualties of War and, just you know, 6 months in the jungle with Sean Penn, you drink cobra blood. It sounded good.

Stewart: Can you milk Sean Penn's fangs and get the juice out of them, or is it-

Fox: I don't know, I've never given it a shot.

Stewart: Next time.

Fox: I was only able to feel for the Cobra.

Stewart: Let me show you something, this a picture,this is the first I've interviewed you on our show, this a picture of it, here's what's crazy, ok, you haven't aged. I look like a child. Look at that, you haven't aged. What the hell is going on here?

Fox: You look sophisticated. I mean I use the Just for Men, which is..

Stewart: I actually color mine grey, I find it adds to the decrepid look I've been going for.

Stewart: Look at this thing [Holds up book] I appreciate this book, because I too suffer from shortness. So I found some inspirational -

Fox: That's it, that's what the title means.

Stewart: How do you, you've been able to keep a pace, a tenacity, with this in terms of bringing awareness to the disease, how do you keep up the energy, focus, the mindset to keep going?

Fox: First of all there is no other choice, you wanna keep going. I love my life I have a great life I have a great family and, um, I just kind of stumbled out of this thing that once I was diagnosed in '91 with PD and I kinda kept it a secret for like 7 years and it was a lot of time to work it out. I did a lot of stupid things, I drank too much, I kinda got crazy with it. It's not like I burst out of a coccoon of ignorance and all of a sudden had a handle on it, but it's like anything, once you accept it and you fix it in space and you say this is this and this is isn't anything else, this is not going to go away anytime soon and I have to deal with it, then you start to open up to all of the stuff thats around it and you say, wow, this gives me an opportunity to help people out, this gives me an opportunity to look at things in a way that I might not have looked at them before and to kind of be a little more serious than the jackass I've been for the past 35 years and writing books and a new kind of appreciation for my family and a relationship with my kids, where I don't have to kind of teach them lessons, hoping they'll pick up things from the way they see me deal with -

Stewart: And how do the kids, cause that's a really interesting thing for kids to see their father be vulnerable. Is it difficult for them? Because, you know, I find that the most difficult thing for my kids is the idea that I'm actually not a superhero, because when they are that little, literally, like, if you can reach a glass up there, they're like, my god..that's like Everest. Have you been able to be vulnerable with them?

Fox: Yeah, absolutely. It just is what it is. They still think your cool in other ways, they know.. With my youngest daughter, to have a conversation with her and just say like my brain works differently than your brain. Your 7 years old and to have that conversation, not that its bad or good or scary or not scary or whatever, it just is that thing. In a way, they love you being honest with them. That's as heroic as you really need to be with your kids, you just need to be honest with them.

Stewart: Your saying I have to be honest with my kids? I'm not sure I can live this book.

Fox: It helps.

Stewart: Dammit. Now what's going on, have you seen any progress, you know, one of the things that you've had to do is, you've gotten involved with the political community, because as somebody who is an activist for cures and an activist for Parkinson's, you've now been exposed to the Washington political community. What's been worse, the diagnosis, having to deal with politicians?

Fox: Politicians are alright. The tricky thing is its like wedge issues, you know how this stuff works, when I get involved with the stem cell thing, its like if you are a conservative republican and stem cells is an issue thats important to you its probably like 3 on your list, you know, its way up there. If you're moderate, democrat, you probably would like to see it happen but its 8 or 9 on your list, so you see politicians know how to work that gap and -

Stewart: I was stunned, you know, when you got involved with it, the idea that your motives could be impuned. That was the craziest part about this this that I ever saw and I've always wondered, I didn't talk to you after that happened but -

Fox: Well that's when it got fun. People think that's when it got bad for me, but that's when it got fun. When Rush Limbaugh, I can barely say the name.

Stewart: So many of us have that issue.

Fox: But when he kind of launched his attack, I just had this moment where I went, oh my god, is that predictable, is it that cartoonish that you attack the messenger in this way and not be with the merits of the science at all, and -

Stewart: Its absolutely that cartoonish.

Fox: It was that cartoonish. But what was great was that it then allowed me to start a dialogue, start a conversation, we basically hijacked the last 2 weeks of that midterm election, talked about stem cells, which nobody wanted to talk about. And it was, other than the fact that I was deadly serious about it, it was kind of like there was a Mary Prankster thing to it -

Stewart: You couldn't believe the theater of it. When your daughter asked you about that, did you have to explain to her, "his brain works differently"? Its diseased.

Fox: That presupposes.

Stewart: Um, as always, its just a pleasure seeing and always a pleasure talking to ya and uh, man, your one of those guys, you walk in a room, and just everybody feels better, I don't know how you do it.

Stewart: Always Looking Up, its on the bookshelves now, Michael J. Fox!


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Good Morning America Skews Farrah Fawcett Story

robin-roberts
On April 7 , 2009 I just happened to stumble across a Good Morning America episode while I was eating breakfast and could not believe what I saw.

Robin Roberts was doing a segment on alternative treatments for cancer involving yoga, attitude, vitamins, etc. after reporting that Farrah Fawcett went to Germany to receive such "alternative treatments."

It has been widely reported that Farrah Fawcett went to Germany to be treated with stem cell therapy, yet Robin Roberts made no mention of this and went on to talk about cancer patients utilizing yoga, natural remedies, and other completely unrelated topics in order to defeat the disease, hinting that Fawcett was doing the same.

This would be fine if Robin Roberts did not imply that Farrah Fawcett was doing these things to treat herself and honestly told the audience that the "alternative" treatment she received in Germany was stem cell therapy and its only been deemed "alternative" because it has been outlawed and stigmatized in the United States.

Subtle lies should not go unnoticed.

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EDIT: At the time of this posting, media reports were claiming that Farrah Fawcett went to Germany for stem cell treatments. This has since been denied by Fawcett and those close to her. The documentary Farrah's Story showed that she went to Germany to receive "additional treatment" to remove tumors from her liver. This involved things like laser treatments to kill the tumors, which is still a far stretch from the comparison Good Morning America was trying to make in its segment.